What Is the Catalytic Mechanism of Enzymatic Histone N-Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Rajeev Ramanan Sodiq O Waheed Christopher J Schofield Christo Z Christov

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2021)

Invited for the cover of this issue are Christo Z. Christov and co-workers at Michigan Technological University and University of Oxford. The image depicts the effects of applying an external electric field on the demethylation of dimethylated arginine substrate by a non-heme Fe center Histone N-methyl arginine demethylase. Read the full text of the article at 10.1002/chem.202101174.

Keyphrases

nitric oxide
amino acid
dna methylation
hydrogen peroxide
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single molecule
crystal structure