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miR-488-3p Protects Cardiomyocytes against Doxorubicin-Induced Cardiotoxicity by Inhibiting CyclinG1.

Mingjing YanYuan CaoQue WangKun XuLin DouXiuqing HuangBeidong ChenWeiqing TangMing LanBing LiuKaiyi ZhuYao YangShenghui SunXiyue ZhangYong ManMingyan HeiTao ShenJian Li
Published in: Oxidative medicine and cellular longevity (2022)
miR-488-3p is one of the important protective miRNAs in doxorubicin-induced cardiotoxicity by inhibiting the expression of CyclinG1, which provides insight into the possible clinical application of miR-488-3p/CyclinG1 as therapeutic targets in doxorubicin-induced cardiovascular diseases.
Keyphrases
  • high glucose
  • diabetic rats
  • drug delivery
  • cardiovascular disease
  • high intensity
  • signaling pathway
  • drug induced
  • poor prognosis
  • cancer therapy
  • oxidative stress
  • cardiovascular risk factors
  • stress induced