Effectiveness of postoperative oral administration of cephalexin and metronidazole on surgical site infection among obese women undergoing cesarean section: a randomized, double-blind, placebo-controlled, parallel-group study-phase III.
Fatemeh TaraSina DanestehMaral RezaeeKiarash Roustai GeraylowAmir Ali Moodi GhalibafSomayeh MoeindarbariPublished in: Antimicrobial resistance and infection control (2022)
Post-operative administration of cephalexin and metronidazole for 48-h post-cesarean delivery among obese women, in addition to the standard pre-operative prophylaxis, reduced the overall rate of surgical site infection and wound infection symptoms in a 2-week follow-up. Trial registration The study protocol was approved by the Iranian Registry of Clinical Trials (IRCTID: IRCT20200608047685N2) on 2021-03-15.
Keyphrases
- surgical site infection
- phase iii
- placebo controlled
- double blind
- clinical trial
- study protocol
- phase ii
- polycystic ovary syndrome
- open label
- randomized controlled trial
- adipose tissue
- weight loss
- metabolic syndrome
- phase ii study
- pregnancy outcomes
- type diabetes
- obese patients
- patients undergoing
- systematic review
- breast cancer risk
- bariatric surgery
- squamous cell carcinoma
- cervical cancer screening
- depressive symptoms