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Aducanumab: a new phase in therapeutic development for Alzheimer's disease?

Giovanna LalliJonathan M SchottJohn A HardyBart De Strooper
Published in: EMBO molecular medicine (2021)
On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer's disease in almost 20 years-and notably, the first drug with a putative disease-modifying mechanism for the treatment of this devastating disorder, namely the removal of β-amyloid (or Aβ) plaques from the brain.
Keyphrases
  • cognitive decline
  • adverse drug
  • emergency department
  • combination therapy
  • blood brain barrier
  • brain injury
  • replacement therapy
  • drug administration