A neural tract-inspired conduit for facile, on-demand biopsy of glioblastoma.
Martha I BetancurAyden CaseEkaterina IlichNalini MehtaSean MeehanSabrina PogrebivskyStephen T KeirKevin StevensonBarun BrahmaSimon GregoryWei ChenDavid M AshleyRavi BellamkondaNassir MokarramPublished in: Neuro-oncology advances (2024)
The results establish the potential of this neural tract-inspired, aligned nanofiber device as an on-demand, safe, and minimally invasive access point, thus enabling rapid, high-throughput, longitudinal assessment of tumor and its microenvironment, ultimately leading to more informed clinical treatment strategies.