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Oral Cladribine in Patients who Change From First-Line Disease Modifying Treatments for Multiple Sclerosis: Protocol of a Prospective Effectiveness and Safety Study (CLAD CROSS).

Georgios TsivgoulisSpyros N DeftereosClaudio GobbiElisabeth Gulowsen CeliusAlina KulakowskaGiorgia ManiscalcoIrene MendesNicolaos Grigoriadis
Published in: Journal of central nervous system disease (2022)
CLAD CROSS will provide efficacy data on cladribine tablets, used as a follow-up treatment to first-line DMDs in the real-world setting, will further establish its safety profile and will collect information to support pharmacoeconomic studies.
Keyphrases
  • multiple sclerosis
  • randomized controlled trial
  • electronic health record
  • white matter
  • machine learning
  • combination therapy
  • case control
  • artificial intelligence