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Digital Instruments for Reporting of Gastrointestinal Symptoms in Clinical Trials: Comparison of End-of-Day Diaries Versus the Experience Sampling Method.

Abraham B BeckersJohanna T W SnijkersZsa Zsa R M WeertsLisa VorkTim KlaassenFabiënne G M SmeetsAdrian A M MascleeDaniel Keszthelyi
Published in: JMIR formative research (2021)
This study demonstrates excellent adherence rates for smartphone app-based end-of-day diaries as used in 2 separate clinical trials. Overall adherence rates for ESM were significantly lower, rendering it more suitable for intermittent sampling periods rather than continuous sampling during longer clinical trials.
Keyphrases
  • clinical trial
  • phase ii
  • double blind
  • open label
  • phase iii
  • randomized controlled trial
  • study protocol
  • adverse drug
  • type diabetes
  • metabolic syndrome
  • insulin resistance
  • weight loss