Changes of NLRP3 in serum and cerebrospinal fluid of patients after moderate to severe traumatic brain injury and their predictive values for prognosis.
Wei ChenZhigang WangGengfan YeGuangyao ZhuShiwei LiPandi ChenHongcai WangShufeng ZouMaosong ChenPublished in: CNS neuroscience & therapeutics (2024)
The levels of NLRP3, especially in the CSF on day 3 post-injury, can serve as a potential biomarker for predicting prognosis in moderate to severe TBI patients. Early measurement of NLRP3 levels can provide valuable insights into patient outcomes and guide therapeutic strategies.