Mena as a key enhancer factor of EMT to promote metastasis of human tongue squamous cell carcinoma.
Hao CuiXiang LiangYifei ZhuSadam Ahmed ElayahHong QiLinyang XieZhichen GuoFang SiyaYu MingGong YuxinJun-Bo TuSi-Jia NaPublished in: Oral diseases (2023)
Mena expression is associated with lymphatic metastasis and tumor stage and promotes TSCC invasion and metastasis by inducing the EMT process. Thus, Mena may be a biomarker for prognosis and targeted therapy in TSCC patients.
Keyphrases
- squamous cell carcinoma
- end stage renal disease
- epithelial mesenchymal transition
- ejection fraction
- newly diagnosed
- chronic kidney disease
- endothelial cells
- poor prognosis
- binding protein
- lymph node
- peritoneal dialysis
- transcription factor
- long non coding rna
- patient reported outcomes
- induced pluripotent stem cells