Expression of phosphorylated estrogen receptor beta is an independent negative prognostic factor for pancreatic ductal adenocarcinoma.
Ioannis PoziosThomas KnöselYue ZhaoGerald AssmannIraklis PoziosMario H MüllerChristiane J BrunsMartin E KreisHendrik SeeligerPublished in: Journal of cancer research and clinical oncology (2018)
Expression of pER-β constitutes an independent prognostic marker for PDAC and is correlated with poor prognosis. These data may help in identifying novel drug targets in PDAC and patients who could benefit from additional therapeutic regimens, including selective estrogen receptor modulators.