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Dually Active Apigenin-Loaded Nanostructured Lipid Carriers for Cancer Treatment.

Lorena Bonilla-VidalMarta ŚwitalskaMarta EspinaJoanna WietrzykMaria Luisa GarcíaEliana B SoutoAnna GliszczyńskaElena Sánchez López
Published in: International journal of nanomedicine (2023)
APG-NLC containing rosehip oil were optimised. They exhibit suitable physicochemical parameters, storage stability for more than 10 months, and prolonged APG release. Moreover, APG-NLC were internalised inside tumour cells, showing the capacity to cause cytotoxicity in cancer cells without damaging healthy cells.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • drug delivery
  • fatty acid
  • endoplasmic reticulum stress
  • oxidative stress
  • cancer therapy