Spatial distribution of cerebral microbleeds reveals heterogeneous pathogenesis in CADASIL.

Ya-Fang ChenChih-Hao ChenWen-Chau WuBo-Ching LeeHsin-Hsi TsaiSung-Chun Tang

Published in: European radiology (2021)

• The topological distribution of lobar CMBs is differentiable between CADASIL and CAA. • In CADASIL patients, hypertension mediates CMB volume and the mediation is region dependent. • CMB risk mapping allows for voxel-wise exploration of CMB distribution and reveals hot spots in the putamen and posteromedial thalamus in CADASIL.

Keyphrases

end stage renal disease
newly diagnosed
blood pressure
ejection fraction
chronic kidney disease
high resolution
prognostic factors
peritoneal dialysis
subarachnoid hemorrhage
social support
patient reported outcomes
cerebral ischemia