Low dose TamOxifen and LifestylE changes for bReast cANcer prevention (TOLERANT study): Study protocol of a randomized phase II biomarker trial in women at increased risk for breast cancer.
Aliana Guerrieri-GonzagaDavide SerranoPatrizia GnagnarellaHarriet JohanssonStefania ZovatoMariateresa NardiMatilde PensabeneSimona BuccoloAndrea DeCensiIrene Maria BriataLuigi PistelliClementina SansoneSara MannucciValentina AristarcoDebora MacisMatteo LazzeroniGaetano AurilioChiara Arianna AccorneroSara GandiniBernardo BonanniPublished in: PloS one (2024)
EuCT number:2023-503994-39-00; Clinical trials.gov NCT06033092.
Keyphrases
- phase ii
- clinical trial
- open label
- study protocol
- low dose
- phase iii
- placebo controlled
- double blind
- randomized controlled trial
- breast cancer risk
- polycystic ovary syndrome
- high dose
- metabolic syndrome
- cardiovascular disease
- breast cancer cells
- physical activity
- type diabetes
- positive breast cancer
- pregnant women
- young adults