Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model.
Erin E Watson EKatrina HuenikenJunhyung LeeShao Hui HuangAmr El MaghrabiWei XuAmy C MorenoChiaojung Jillian TsaiEzra HahnAndrew J McPartlinChristopher M K L YaoDavid P GoldsteinJohn R De AlmeidaJohn N WaldonClifton David FullerAndrew J HopeSalvatore L RuggieroMichael GlogauerAli A HosniPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
We identified risk factors for ORN and proposed a novel ORN classification system on the basis of vertical extent of bone necrosis and presence/absence of exposed bone/fistula. It outperformed existing systems in depicting the seriousness of ORN and may facilitate clinical care and clinical trials.