Immune Checkpoints Receptors Expression of Macrophage/Monocytes in Response to Acute Viral Respiratory Infection.
Asmaa ZahranHosni A HusseinAli A ThabetMohamed R IzzaldinAhmed A WardanyAli SobhyMohamed A BashirMagdy M AfifiWageeh A AliAmal RayanKhaled SaadMohammad Gamal KhalafMahmoud Elsaeed AhmedNoha G SayedPublished in: Journal of clinical medicine research (2024)
The examination of clinical specimens obtained from patients with signs of acute respiratory viral infection showed the role of the macrophage in the immune response. Dysfunction in macrophages results in heightened immune activity and inflammation, which plays a role in the progression of viral diseases and the emergence of accompanying health issues. This malfunction in macrophages is a common characteristic seen in various viruses, making it a promising focus for antiviral therapies with broad applicability. The immune checkpoint could be a target for immune modulation in patients with severe symptoms.
Keyphrases
- liver failure
- immune response
- respiratory failure
- sars cov
- oxidative stress
- drug induced
- adipose tissue
- public health
- poor prognosis
- healthcare
- dendritic cells
- aortic dissection
- mental health
- early onset
- hepatitis b virus
- respiratory tract
- binding protein
- risk assessment
- long non coding rna
- toll like receptor
- inflammatory response
- mechanical ventilation
- fine needle aspiration