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[Importance of HPV status and p16 for the prognosis of penile carcinoma].

Jan Niklas MinkOybek KhalmurzaevAlexey PryalukhinSebastian HöltersCarol GeppertStefan LohseKristof BendeJoão LoboRui HenriqueHagen LoertzerJoachim SteffensCarmen JerónimoHeiko WunderlichJulia HeinzelbeckerRainer BohleMichael StöckleVsevolod MatveevArndt HartmannKerstin Junker
Published in: Aktuelle Urologie (2023)
HPV status alone seems to be lacking prognostic relevance. In contrast, p16 status was confirmed as an independent prognostic factor. Thus, the expression of p16INK4a is associated with a significantly better MFS. Especially in HPV-negative tumours, the p16 status should be evaluated with regard to the prognostic value and thus also with a view to the treatment decision.
Keyphrases
  • prognostic factors
  • high grade
  • poor prognosis
  • magnetic resonance
  • magnetic resonance imaging
  • prostate cancer
  • combination therapy