Single Nucleotide Variants in KIF14 Gene May Have Prognostic Value in Breast Cancer.

Ivona KrusVeronika BrynychováViktor HlaváčRadka VáclavíkováMaria KováčováRenata KoževnikovováKaterina KopečkováJannis TornikidisDavid VránaJiří GatěkPavel Souček

Published in: Molecular diagnosis & therapy (2022)

In conclusion, our preliminary data suggest that minor alleles in rs17448931 and rs3806362 of KIF14 represent candidate biomarkers of poor prognosis of breast cancer patients. After pending validation in independent populations and eventual functional characterization, these candidates might become useful biomarkers in the clinics.

Keyphrases

poor prognosis
long non coding rna
copy number
primary care
electronic health record
genome wide
transcription factor
machine learning
young adults
artificial intelligence
data analysis
genetic diversity