Diagnostic Accuracy of Group A Streptococcus Rapid Antigen Detection Test on Middle Ear Fluid in Children With Acute Otitis Media With Spontaneous Perforation: A Prospective Multicenter Evaluation.
Robert CohenEmmanuelle VaronPhilippe BidetJérémie F CohenStéphane BéchetVincent CouloignerAnne Sylvestre MichotCécile GuiheneufStéphane BonacorsiCorinne LevyPublished in: The Pediatric infectious disease journal (2023)
Group A Streptococcus is one of the leading causes of otorrhea. The performance of rapid antigen tests in 256 children with otorrhea showed excellent sensitivity, 97.3% (95% confidence interval: 90.7%-99.7%), and specificity, 100% (95% confidence interval: 98.0%-100%). In a period of increasing invasive and noninvasive group A Streptococcus infections, an early diagnosis could be useful.