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A pilot, masked, randomized controlled trial to evaluate local gentamicin versus saline in open tibial fractures (pGO-Tibia).

Billy T HaongaPatrick NgunyaleEricka P von KaepplerClaire A DonnelleyNae Y WonEdmund N EliezerKelsey BrownMichael FloresJamieson M O'MarrPatricia RodarteMayur UrvaAbigail CortezTravis PorcoSaam MorshedDavid W Shearer
Published in: OTA international : the open access journal of orthopaedic trauma (2023)
This pilot study is among the first to evaluate locally administered gentamicin in open tibial fractures. Results indicate a rigorous clinical trial with acceptable rates of enrollment and follow-up to address this topic is possible in this setting.
Keyphrases
  • study protocol
  • randomized controlled trial
  • total knee arthroplasty
  • clinical trial
  • minimally invasive
  • open label
  • anterior cruciate ligament reconstruction
  • health insurance
  • phase ii
  • double blind
  • phase iii