Upregulation of MicroRNA-125b Leads to the Resistance to Inflammatory Injury in Endothelial Progenitor Cells.
Ke YangXing LiuWanwen LinYuanyuan ZhangChaoquan PengPublished in: Cardiology research and practice (2020)
miR-125b protects EPCs against TNF-α-induced inflammation and cell apoptosis by attenuating the activation of NF-κB pathway and consequently improves the cardiac function recovery and EPC-mediated neovascularization in the ischemic hearts.
Keyphrases
- oxidative stress
- diabetic rats
- signaling pathway
- cell proliferation
- high glucose
- ischemia reperfusion injury
- endothelial cells
- rheumatoid arthritis
- poor prognosis
- lps induced
- vascular endothelial growth factor
- pi k akt
- nuclear factor
- drug induced
- diabetic retinopathy
- toll like receptor
- immune response
- blood brain barrier