Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response.

Soumyadeep SarkarEmily C ElliottHayden R HenryIvo Díaz LudovicoJohn T Melchior Ashley Frazer-Abel Bobbie-Jo M Webb-Robertson William Sean Davidson V Michael Holers Marian J Rewers Thomas O Metz Ernesto S Nakayasu

Published in: medRxiv : the preprint server for health sciences (2023)

Biomarkers analyzed in this systematic review highlight alterations in specific biological processes in T1D, including complement, lipid metabolism, and immune response pathways, and may have potential for further use in the clinic as prognostic or diagnostic assays.

Keyphrases

systematic review
immune response
type diabetes
meta analyses
primary care
cardiovascular disease
dendritic cells
toll like receptor
randomized controlled trial
high throughput
metabolic syndrome
risk assessment
adipose tissue
climate change
skeletal muscle