Pregnancy-associated plasma protein A - a new indicator of pulmonary vascular remodeling in chronic thromboembolic pulmonary hypertension?

Steffen D KriechbaumFelix RudolphChristoph B WiedenrothLisa MielzarekMoritz HaasStefan GuthChristian W HammEckhard MayerChristoph LiebetrauSteffen D Kriechbaum

Published in: Respiratory research (2020)

PAPP-A is overexpressed in CTEPH and decrease significantly after surgical or interventional therapy, however without association to hemodynamics. Further investigation is needed to define the underlying mechanism of PAPP-A expression and changes after therapy in CTEPH.

Keyphrases

pulmonary hypertension
poor prognosis
pulmonary artery
binding protein
atrial fibrillation
preterm birth
protein protein