High expression of PD-L1 on conventional dendritic cells in tumour-draining lymph nodes is associated with poor prognosis in oral cancer.
Hjalmarsson EricKrzysztof PiersialaVilma LagebroPedro Farrajota Neves Da SilvaMarianne PetroMagnus StarkhammarAlexandra ElliotRusana BarkGregori MargolinSusanna Kumlien GeorénLars-Olaf CardellPublished in: Cancer immunology, immunotherapy : CII (2024)
T-cells. The detection of high PDL1 expression on cDC1s was indicative of TDLN metastasis and an adverse prognosis, proposing that PD-L1 on dendritic cells in TDLN could serve as a predictive biomarker of OSCC patients with a worse prognosis.