Effectiveness of ocriplasmin in real-world settings: A systematic literature review, meta-analysis, and comparison with randomized trials.

Arshad M KhananiRyan N ConstantineKoenraad H Blot Benedicte LescrauwaetPeter Szurman

Published in: Acta ophthalmologica (2020)

Ocriplasmin was significantly more effective in achieving nsVMAR in RWS than in RCTs. Lower ERM prevalence in RWS was the single significant explanatory variable for this difference. Conclusions on ocriplasmin safety in RWS are limited due to inconsistent reporting.

Keyphrases

systematic review
randomized controlled trial
meta analyses
risk factors
adverse drug
emergency department
case control