Over-expression of both VEGF-C and Twist predicts poor prognosis in human breast cancer.

Y-Q ZhangW-L ChenF ZhangX-L WeiD ZengY-K LiangJ-D WuL-Y ZhangC-P GuoH-C ZengS-S HaoR-H LiW-H HuangGuo-Jun Zhang

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2019)

Our results suggested that co-expression of VEGF-C and Twist was associated with larger tumor size, higher numbers of lymph node involvement, D2-40-positive LVI, higher risk of distant metastasis, and worse DFS or OS in breast cancer patients.

Keyphrases

poor prognosis
lymph node
endothelial cells
long non coding rna
vascular endothelial growth factor
epithelial mesenchymal transition
neoadjuvant chemotherapy
induced pluripotent stem cells
sentinel lymph node
early stage
breast cancer risk