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The use of onabotulinumtoxinA to treat idiopathic overactive bladder in elderly patients is in need of study.

Kate MannsAsher KhanKevin V CarlsonAdrian S WaggRichard J BaverstockR Trafford Crump
Published in: Neurourology and urodynamics (2021)
While the initial systematic review did not generate the expected results, it did reveal that age-related outcomes of BoTN-A for the treatment of OAB are significantly under-studied. Given that the prevalence of OAB increases with age, this is an important knowledge gap. Our article explains the rationale for further study in this area.
Keyphrases
  • systematic review
  • clinical trial
  • randomized controlled trial
  • meta analyses
  • type diabetes
  • dna methylation
  • adipose tissue
  • metabolic syndrome
  • replacement therapy
  • smoking cessation
  • glycemic control