A single-arm, phase 2 study of steroid-containing mouthwash for the prevention of everolimus-associated stomatitis in multiple tumor types.
Masaya HattoriSumitaka HagiwaraHaruru KotaniMichiko TatematsuMasahiko TachiSusumu HijiokaJunichi ShimizuMasashi AndohYasunari MizunoMasataka SawakiAkiyo YoshimuraNaomi GondoYayoi AdachiKenichi YoshimuraHiroji IwataPublished in: International journal of clinical oncology (2019)
Our findings did not support a prophylactic effect of steroid-containing mouthwash on everolimus-associated stomatitis. Given the needs of prevention of everolimus-associated stomatitis in various tumor types, further studies in a larger population using a randomized controlled trial design are, therefore, required to confirm the efficacy of steroid-containing mouthwash.