Association Between Frequency of Social Contact and Brain Atrophy in Community-Dwelling Older People Without Dementia: The JPSC-AD Study.

Naoki HirabayashiTakanori HondaJun HataYoshihiko FurutaMao ShibataTomoyuki OharaYasuko TatewakiYasuyuki TakiShigeyuki NakajiTetsuya MaedaKenjiro OnoMasaru MimuraKenji NakashimaJun-Ichi IgaMinoru TakebayashiToshiharu Ninomiyanull null

Published in: Neurology (2023)

Lower frequency of social contact was associated with decreased total and cognitive function-related regional brain volumes. In addition, depressive symptoms partially explained the association in community-dwelling older people without dementia in Japan.

Keyphrases

community dwelling
depressive symptoms
mild cognitive impairment
resting state
white matter
healthcare
cognitive impairment
mental health
functional connectivity
cerebral ischemia
social support
sleep quality
blood brain barrier