Intestinal Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment.
Alexandria M DoerflerJun HanKelsey E JarrettLi TangAntrix JainAlexander B SaltzmanMarco De GiorgiMarcel ChuecosAyrea E HurleyAng LiPauline MorandClaudia AyalaDavid R GoodlettAnna MalovannayaJames F MartinThomas Q de Aguiar VallimNoah ShroyerWilliam R LagorPublished in: Arteriosclerosis, thrombosis, and vascular biology (2022)
in the intestine is compatible with life through compensatory increases in intestinal absorptive surface area, LDLR expression, and expansion of the resident stem cell compartment.