Functional Connectivity Favors Aberrant Visual Network c-Fos Expression Accompanied by Cortical Synapse Loss in a Mouse Model of Alzheimer's Disease.
Oliver J L'EsperanceJoshua McGheeGarett DavidsonSuraj NiraulaAdam S SmithAlexandre A SosunovShirley Shidu YanJaichandar SubramanianPublished in: Journal of Alzheimer's disease : JAD (2024)
Visual network structural and functional disruptions are biased toward cortical regions in pre-plaque J20 mice, and the cellular and synaptic dysregulation in the AD-model represents a maladaptive modification of the baseline physiology seen in WT conditions.