Immunoglobulin E Sensitization to Mammalian Oligosaccharide Galactose-α-1,3 (α-Gal) Is Associated With Noncalcified Plaque, Obstructive Coronary Artery Disease, and ST-Segment-Elevated Myocardial Infarction.
Stephen T VernonKatharine A KottThomas HansenMeghan FinemoreKarl W BaumgartRavinay BhindiJean Yee Hwa YangPeter S HansenStephen J NichollsDavid S CelermajerMichael R WardSheryl A van NunenStuart M GrieveGemma A FigtreePublished in: Arteriosclerosis, thrombosis, and vascular biology (2022)
α-Gal sensitization is independently associated with noncalcified plaque burden and obstructive CAD and occurs at higher frequency in patients with STEMI than those with stable or no CAD. These findings may have implications for individuals exposed to ticks, as well as public health policy. Registration: URL: https://www.anzctr.org.au; Unique identifier: ACTRN12618001322224.
Keyphrases
- coronary artery disease
- public health
- percutaneous coronary intervention
- cardiovascular events
- coronary artery bypass grafting
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- heart failure
- healthcare
- left ventricular
- sensitive detection
- risk factors
- aortic stenosis
- cardiovascular disease
- acute coronary syndrome
- visible light