Effects of histone acetyltransferase (HAT) and histone deacetylase (HDAC) inhibitors on proliferative, differentiative, and regenerative functions of Toll-like receptor 2 (TLR-2)-stimulated human dental pulp cells (hDPCs).
Sarah Hossam FahmyHolger JungbluthSøeren JepsenJochen WinterPublished in: Clinical oral investigations (2023)
Targeting hDPC nuclear function could be a promising option in the scope of the biological management of inflammatory pulp diseases.
Keyphrases
- toll like receptor
- histone deacetylase
- inflammatory response
- nuclear factor
- induced apoptosis
- immune response
- stem cells
- endothelial cells
- cell cycle arrest
- oxidative stress
- mesenchymal stem cells
- dna methylation
- cell therapy
- induced pluripotent stem cells
- endoplasmic reticulum stress
- pluripotent stem cells
- gene expression
- cell death