Effect of exercise on neuromuscular toxicity in oxaliplatin-treated mice.

Justin G LeesMunawwar AbdullaMallory E Barkl-LukeLital LivniBrooke A KeatingJessica HayesNathan T FioreSusanna B ParkGila Moalem-TaylorDavid Goldstein

Published in: Muscle & nerve (2021)

Exercise intervention did not improve signs of peripheral neuropathy but moderately reduced the negative impact of oxaliplatin chemotherapy related to muscle morphology, suggesting the potential for exploring the impact of exercise on reducing oxaliplatin-induced neuromuscular toxicity in cancer patients.

Keyphrases

high intensity
physical activity
resistance training
oxidative stress
randomized controlled trial
skeletal muscle
high glucose
diabetic rats
type diabetes
radiation therapy
insulin resistance