Sida rhombifolia Exerts Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer HepG2 Cells in Vitro.

Mohadeseh AhmadiMohammad Ali EbrahimzadehAlireza RafieiMostafa KardanMohammad Ali Ebrahimi

Published in: Asian Pacific journal of cancer prevention : APJCP (2022)

In conclusion, the EtOAc extract of S. rhombifolia is capable of inducing apoptosis in HepG2 cells through modulation of the mitochondrial pathway, which explains their antitumor activity.

Keyphrases

oxidative stress
anti inflammatory
cell death
endothelial cells
cell cycle arrest
endoplasmic reticulum stress
induced pluripotent stem cells
pluripotent stem cells
signaling pathway
cell proliferation