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Application of the Movement Disorder Society prodromal criteria in healthy G2019S-LRRK2 carriers.

Anat MirelmanRachel Saunders-PullmanRoy N AlcalayShiran ShustakAvner ThalerTanya GurevichDeborah RaymondHelen Mejia-SantanaMartha Orbe ReillyLaurie OzeliusLorraine ClarkMali Gana-WeiszAnat Bar-ShiraAvi Orr-UtregerSusan B BressmanKaren MarderNir Giladinull null
Published in: Movement disorders : official journal of the Movement Disorder Society (2018)
The results showed the utility of using the criteria and high sensitivity and specificity in identifying prodromal PD in this high-risk unique cohort. These results may be valuable for future disease modification clinical trials. © 2018 International Parkinson and Movement Disorder Society.
Keyphrases
  • clinical trial
  • parkinson disease
  • current status
  • randomized controlled trial
  • phase ii
  • structural basis