The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review.
Panagiotis SkourasTheodosis KalamatianosMariam MarkouliAngelos KaragiannisLampis C StavrinouPublished in: CNS & neurological disorders drug targets (2023)
The limitations reported by several meta-analyses, included low patient numbers or disproportionate representation of patients from certain RCTs, differences in drug treatment, patient diagnostic criteria and outcome evaluation between RCTs, as well as poor data quality or lack of RCTs data. Knowledge of the reported limitations may aid the design of future clinical trials and/or their meta-analyses.
Keyphrases
- meta analyses
- systematic review
- randomized controlled trial
- clinical trial
- end stage renal disease
- case report
- ejection fraction
- electronic health record
- healthcare
- newly diagnosed
- big data
- chronic kidney disease
- cardiovascular disease
- peritoneal dialysis
- prognostic factors
- single cell
- study protocol
- patient reported outcomes
- quality improvement
- machine learning
- artificial intelligence
- data analysis
- deep learning
- drug induced
- patient reported