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Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development.

Rosane MazzarellaKarina Cañón-BeltránYulia N CajasMeriem HamdiEncina M GonzálezJuliano C da SilveiraClaudia L V LealDimitrios Rizos
Published in: Journal of animal science and biotechnology (2024)
Our study suggests that miRNAs within OF- and UF-EVs could modulate bovine embryo development and quality, providing insights into the intricate maternal-embryonic communication that might be involved in modulating lipid metabolism, immune response, and implantation during early pregnancy.
Keyphrases
  • immune response
  • signaling pathway
  • pregnancy outcomes
  • fatty acid
  • dendritic cells
  • epithelial mesenchymal transition
  • pregnant women
  • body mass index
  • inflammatory response
  • preterm birth