Blocking the TRAIL-DR5 Pathway Reduces Cardiac Ischemia-Reperfusion Injury by Decreasing Neutrophil Infiltration and Neutrophil Extracellular Traps Formation.
Xuance WangRan XieDan ZhaoGuiling WangLijie ZhangWei ShiYanyan ChenTingting MoYuxin DuXuefei TianWanjun WangRun CaoYuanfang MaYinxiang WeiYaohui WangPublished in: Cardiovascular drugs and therapy (2024)
This work clarifies how the TRAIL-DR5 signaling pathway regulates the neutrophil response during myocardial I/R damage, thereby providing a scientific basis for therapeutic intervention targeting the TRAIL-DR5 signaling pathway in myocardial infarction.