Urinary 8-hydroxy-2'-deoxyguanosine levels and preterm births: a prospective cohort study from the Japan Environment and Children's Study.

Tsuyoshi MurataHyo KyozukaToma FukudaKarin ImaizumiHirotaka IsogamiAya KannoShun YasudaAkiko YamaguchiAkiko SatoYuka OgataKosei ShinokiMitsuaki HosoyaSeiji YasumuraKoichi HashimotoHidekazu NishigoriKeiya Fujimorinull null

Published in: BMJ open (2024)

High U8-OHdG levels were associated with increased PTB incidence, especially in participants without representative causes for artificial PTB. Our results can help identify the mechanisms leading to PTB, considering the variable aetiologies of this condition; further validation is needed to clarify clinical impacts.

Keyphrases

gestational age
young adults
risk factors
preterm birth
cross sectional