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Tumour infiltrating lymphocytes and survival after adjuvant chemotherapy in patients with gastric cancer: post-hoc analysis of the CLASSIC trial.

Drolaiz H W LiuYoung-Woo KimNina SefcovicovaJon P LayeLindsay C HewittAndrew F IrvineVincent VromenYannick JanssenNaser DavarzaniGregorio E FazziShahab JolaniVeerle MelotteDerek R MageeMyeong-Cherl KookHyunki KimRupert LangerJae-Ho CheongHeike I Grabsch
Published in: British journal of cancer (2023)
This is the first study to suggest TIL density automatically quantified in routine HE stained tissue sections as a novel, clinically useful biomarker to identify stage II-III GC patients deriving benefit from adjuvant chemotherapy. Validation of our results in a prospective study is warranted.
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