Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer.

Yingming LiRendong YangChristine M HenzlerYeung HoCourtney PassowBenjamin AuchSuzanne CarreiraDaniel Nava RodriguesClaudia BertanTae Hyun HwangDavid A QuigleyHa X DangColm MorrisseyMichael FraserStephen R PlymateChristopher A MaherFelix Y FengJohann S de BonoScott M Dehm

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

AR gene rearrangements are an important mechanism of resistance to endocrine therapies in CRPC.

Keyphrases

prostate cancer
copy number
genome wide
squamous cell carcinoma
genome wide identification
radical prostatectomy
gene expression
transcription factor
genome wide analysis