Scott M Dehm

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Topics

Dna Methylation

Radical Prostatectomy

Gene Expression

Top Venues

Nature communications

Nature genetics

Science advances

Cancer research communications

This page only lists publications with an associated author ORCID identifier.

Publications

Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics (2024)
Cristina Maranto, Lavannya Sabharwal, Vindhya Udhane, Samuel P Pitzen, Braedan M McCluskey, Songyan Qi, Christine O'Connor, Savita Devi, Scott Johnson, Kenneth Jacobsohn, Anjishnu Banerjee, Kenneth A Iczkowski, Liang Wang, Scott M Dehm, Marja T Nevalainen
Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling. Science advances 10 (9) (2024)
Weijie Zhang, Adam M Lee, Lauren Lee, Scott M Dehm, Rong Stephanie Huang
Computational drug discovery pipelines identify NAMPT as a therapeutic target in neuroendocrine prostate cancer. Clinical and translational science 17 (9) (2024)
Carly D Miller, John R Lozada, Nicholas A Zorko, Andrew Elliott, Allison Makovec, Milan Radovich, Elisabeth I Heath, Archana M Agarwal, Rana R McKay, Rohan Garje, Bruno R Bastos, Dave S B Hoon, Jacob J Orme, A Oliver Sartor, Ari M VanderWalde, Chadi Nabhan, George W Sledge, Eugene Shenderov, Scott M Dehm, Emil Lou, Jeffrey S Miller, Justin H Hwang, Emmanuel S Antonarakis
Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target Across Human Malignancies. Cancer research communications 4 (5) (2024)
Zicheng Wang, Yunong Xia, Lauren Mills, Athanasios N Nikolakopoulos, Nicole Maeser, Scott M Dehm, Jason M Sheltzer, Ruping Sun
Evolving copy number gains promote tumor expansion and bolster mutational diversification. Nature communications 15 (1) (2024)
Zicheng Wang, Yunong Xia, Lauren Mills, Athanasios N Nikolakopoulos, Nicole Maeser, Scott M Dehm, Jason M Sheltzer, Ruping Sun
Evolving copy number gains promote tumor expansion and bolster mutational diversification. Nature communications 15 (1) (2024)
Cristina Maranto, Lavannya Sabharwal, Vindhya Udhane, Samuel P Pitzen, Braedan M McCluskey, Songyan Qi, Christine O'Connor, Savita Devi, Scott Johnson, Kenneth Jacobsohn, Anjishnu Banerjee, Kenneth A Iczkowski, Liang Wang, Scott M Dehm, Marja T Nevalainen
Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling. Science advances 10 (9) (2024)
Zicheng Wang, Yunong Xia, Lauren Mills, Athanasios N Nikolakopoulos, Nicole Maeser, Scott M Dehm, Jason M Sheltzer, Ruping Sun
Evolving copy number gains promote tumor expansion and bolster mutational diversification. Nature communications 15 (1) (2024)
Carly D Miller, John R Lozada, Nicholas A Zorko, Andrew Elliott, Allison Makovec, Milan Radovich, Elisabeth I Heath, Archana M Agarwal, Rana R McKay, Rohan Garje, Bruno R Bastos, Dave S B Hoon, Jacob J Orme, A Oliver Sartor, Ari M VanderWalde, Chadi Nabhan, George W Sledge, Eugene Shenderov, Scott M Dehm, Emil Lou, Jeffrey S Miller, Justin H Hwang, Emmanuel S Antonarakis
Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target across Human Malignancies. Cancer research communications (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Cristina Maranto, Lavannya Sabharwal, Vindhya Udhane, Samuel P Pitzen, Braedan M McCluskey, Songyan Qi, Christine O'Connor, Savita Devi, Scott Johnson, Kenneth Jacobsohn, Anjishnu Banerjee, Kenneth A Iczkowski, Liang Wang, Scott M Dehm, Marja T Nevalainen
Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling. Science advances 10 (9) (2024)
Carly D Miller, John R Lozada, Nicholas A Zorko, Andrew Elliott, Allison Makovec, Milan Radovich, Elisabeth I Heath, Archana M Agarwal, Rana R McKay, Rohan Garje, Bruno R Bastos, Dave S B Hoon, Jacob J Orme, A Oliver Sartor, Ari M VanderWalde, Chadi Nabhan, George W Sledge, Eugene Shenderov, Scott M Dehm, Emil Lou, Jeffrey S Miller, Justin H Hwang, Emmanuel S Antonarakis
Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target Across Human Malignancies. Cancer research communications 4 (5) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Shuang G Zhao, Matthew Bootsma, Stanley Zhou, Raunak Shrestha, Thaidy Moreno-Rodriguez, Arian Lundberg, Chu Pan, Christopher Arlidge, James R Hawley, Adam Foye, Alana S Weinstein, Martin Sjostrom, Meng Zhang, Haolong Li, Lisa N Chesner, Nicholas R Rydzewski, Kyle T Helzer, Yue Shi, null null, Molly Lynch, Scott M Dehm, Joshua M Lang, Joshi J Alumkal, Housheng Hansen He, Alexander W Wyatt, Rahul R Aggarwal, Wilbert Zwart, Eric J Small, David A Quigley, Mathieu Lupien, Felix Y Feng
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Nature genetics 56 (8) (2024)
Hannah E Bergom, Ashraf Shabaneh, Abderrahman Day, Atef Ali, Ella Boytim, Sydney Tape, John R Lozada, Xiaolei Shi, Carlos Perez Kerkvliet, Sean McSweeney, Samuel P Pitzen, Megan Ludwig, Emmanuel S Antonarakis, Justin M Drake, Scott M Dehm, Charles J Ryan, Jinhua Wang, Justin H Hwang
ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems. Communications biology 6 (1) (2023)
Chitra Rawat, Salma Ben-Salem, Nidhi Singh, Gaurav Chauhan, Anja Rabljenovic, Vishwa Vaghela, Varadha Balaji Venkadakrishnan, Jonathan D Macdonald, Ujjwal Ranjan Dahiya, Yara Ghanem, Salam P Bachour, Yixue Su, Adam D DePriest, Sanghee Lee, Michelle Muldong, Hyun Tae Kim, Sangeeta Kumari, Malyn May Valenzuela, Dingxiao Zhang, Qiang Hu, Eduardo Cortes Gomez, Scott M Dehm, Amina Zoubeidi, Christina A M Jamieson, Marlo Nicolas, Jesse K McKenney, Belinda B Willard, Eric E Klein, Cristina Magi-Galluzzi, Shaun R Stauffer, Song Liu, Hannelore V Heemers
Prostate cancer progression relies on the mitotic kinase citron kinase. Cancer research (2023)
Jamie M Sperger, Kyle T Helzer, Charlotte N Stahlfeld, Dawei Jiang, Anupama Singh, Katherine R Kaufmann, David J Niles, Erika Heninger, Nicholas R Rydzewski, Liguo Wang, Liewei Wang, Rendong Yang, Yanan Ren, Johnathan W Engle, Peng Huang, Christos E Kyriakopoulos, Susan F Slovin, Howard R Soule, Shuang G Zhao, Manish Kohli, Scott T Tagawa, Weibo Cai, Scott M Dehm, Joshua M Lang
Expression and therapeutic targeting of Trop-2 in treatment resistant prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Samuel P Pitzen, Scott M Dehm
Basal epithelial cells in prostate development, tumorigenesis, and cancer progression. Cell cycle (Georgetown, Tex.) (2023)
Andrej Zivanovic, Jeffrey T Miller, Sarah A Munro, Todd P Knutson, Yingming Li, Courtney N Passow, Pijus Simonaitis, Molly Lynch, LeAnn Oseth, Shuang G Zhao, Felix Y Feng, Pernilla Wikström, Eva Corey, Colm Morrissey, Christine Henzler, Benjamin J Raphael, Scott M Dehm
Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer. NAR cancer 5 (3) (2023)
Brooke R Druliner, Krishna R Kalari, Sisi Qin, Scott M Dehm, Vipul Bhargava, Michael Gormley, Winston Tan, Jason P Sinnwell, David W Hillman, Ying Li, Peter T Vedell, Rachel E Carlson, Alan H Bryce, Raphael E Jimenez, Richard M Weinshilboum, Manish Kohli, Liewei Wang
Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment. Molecular cancer research : MCR 20 (12) (2022)
Meixia Che, Aashi Chaturvedi, Sarah A Munro, Samuel P Pitzen, Alexander L Ling, Weijie Zhang, Josh Mentzer, Sheng Yu Ku, Loredana Puca, Yanyun Zhu, Andries M Bergman, Tesa M Severson, Colleen Forster, Yuzhen Liu, Jacob Hildebrand, Mark Daniel, Ting-You Wang, Luke A Selth, Theresa E Hickey, Amina Zoubeidi, Martin Gleave, Rohan Bareja, Andrea Sboner, Wayne D Tilley, Jason S Carroll, Winston Tan, Manish Kohli, Rendong Yang, Andrew C Hsieh, Paari Murugan, Wilbert Zwart, Himisha Beltran, Rong Stephanie Huang, Scott M Dehm
Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer. Nature communications 12 (1) (2021)
Yingming Li, Rendong Yang, Christine M Henzler, Yeung Ho, Courtney Passow, Benjamin Auch, Suzanne Carreira, Daniel Nava Rodrigues, Claudia Bertan, Tae Hyun Hwang, David A Quigley, Ha X Dang, Colm Morrissey, Michael Fraser, Stephen R Plymate, Christopher A Maher, Felix Y Feng, Johann S de Bono, Scott M Dehm
Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (8) (2020)
Shuang G Zhao, William S Chen, Haolong Li, Adam Foye, Meng Zhang, Martin Sjostrom, Rahul Aggarwal, Denise Playdle, Arnold Liao, Joshi J Alumkal, Rajdeep Das, Jonathan Chou, Junjie T Hua, Travis J Barnard, Adina M Bailey, Eric D Chow, Marc D Perry, Ha X Dang, Rendong Yang, Ruhollah Moussavi-Baygi, Li Zhang, Mohammed Alshalalfa, S Laura Chang, Kathleen E Houlahan, Yu-Jia Shiah, Tomasz M Beer, George Thomas, Kim N Chi, Martin Gleave, Amina Zoubeidi, Robert E Reiter, Matthew B Rettig, Owen Witte, M Yvonne Kim, Lawrence Fong, Daniel E Spratt, Todd M Morgan, Rohit Bose, Franklin W Huang, Hui Li, Lisa Chesner, Tanushree Shenoy, Hani Goodarzi, Irfan A Asangani, Shahneen Sandhu, Joshua M Lang, Nupam P Mahajan, Primo N Lara, Christopher P Evans, Phillip Febbo, Serafim Batzoglou, Karen E Knudsen, Housheng Hansen He, Jiaoti Huang, Wilbert Zwart, Joseph F Costello, Jianhua Luo, Scott A Tomlins, Alexander W Wyatt, Scott M Dehm, Alan Ashworth, Luke A Gilbert, Paul C Boutros, Kyle Kai-How Farh, Sunita Shankar, Christopher A Maher, Eric J Small, David A Quigley, Felix Y Feng
The DNA methylation landscape of advanced prostate cancer. Nature genetics 52 (8) (2020)
Abdallah M Eteleeb, David A Quigley, Shuang G Zhao, Duy Pham, Rendong Yang, Scott M Dehm, Jingqin R Luo, Felix Y Feng, Ha X Dang, Christopher A Maher
SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression. Scientific reports 10 (1) (2020)
Paige M Glumac, Joseph P Gallant, Mariya Shapovalova, Yingming Li, Paari Murugan, Shilpa Gupta, Ilsa M Coleman, Peter S Nelson, Scott M Dehm, Aaron M LeBeau
Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (5) (2019)
Mariya Shapovalova, John K Lee, Yingming Li, Donald J Vander Griend, Ilsa M Coleman, Peter S Nelson, Scott M Dehm, Aaron M LeBeau
PEG10 Promoter-Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer. Cancer research 79 (21) (2019)
Varadha Balaji Venkadakrishnan, Adam D DePriest, Sangeeta Kumari, Dhirodatta Senapati, Salma Ben-Salem, Yixue Su, Giridhar Mudduluru, Qiang Hu, Eduardo Cortes, Elena Pop, James L Mohler, Gissou Azabdaftari, Kristopher Attwood, Rajal B Shah, Christina Jamieson, Scott M Dehm, Cristina Magi-Galluzzi, Eric E Klein, Nima Sharifi, Song Liu, Hannelore V Heemers
Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy. Oncogene 38 (23) (2019)
Anne Y Warren, Charles E Massie, Kate Watt, Katarina Luko, Folake Orafidiya, Luke A Selth, Hisham Mohammed, Brinder S Chohan, Suraj Menon, Ajoeb Baridi, Wanfeng Zhao, Carles Escriu, Thanakorn Pungsrinont, Clive D'Santos, Xiaoping Yang, Chris Taylor, Arham Qureshi, Vincent R Zecchini, Greg L Shaw, Scott M Dehm, Ian G Mills, Jason S Carroll, Wayne D Tilley, Iain J McEwan, Aria Baniahmad, David E Neal, Mohammad Asim
A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer. Oncogene 38 (7) (2018)
Christine Henzler, Yingming Li, Rendong Yang, Terri McBride, Yeung Ho, Cynthia Sprenger, Gang Liu, Ilsa Coleman, Bryce Lakely, Rui Li, Shihong Ma, Sean R Landman, Vipin Kumar, Tae Hyun Hwang, Ganesh V Raj, Celestia S Higano, Colm Morrissey, Peter S Nelson, Stephen R Plymate, Scott M Dehm
Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer. Nature communications 7 (2016)