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Exosomes-Coated miR-34a Displays Potent Antitumor Activity in Pancreatic Cancer Both in vitro and in vivo.

Ling ZuoHongyu TaoHuanli XuCong LiGan QiaoMingyue GuoShousong CaoMinghua LiuXiukun Lin
Published in: Drug design, development and therapy (2020)
ExomiR-34a can inhibit the growth of pancreatic cancer both in vitro and in vivo. Targeting miR-34a is a promising strategy for the treatment of pancreatic cancer. ExomiR-34a has the potential to be developed as a novel anticancer agent for the treatment of human pancreatic malignancy.
Keyphrases
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • mesenchymal stem cells
  • combination therapy
  • risk assessment
  • drug delivery
  • cancer therapy
  • replacement therapy
  • pluripotent stem cells