Intramolecular radical cyclization approach to access highly substituted indolines and 2,3-dihydrobenzofurans under visible-light.
Clarice A D CaiubyAkbar AliVinicius T SantanaFrancisco W S LucasMarilia S SantosArlene Gonçalves CorrêaOtaciro R NascimentoHao JiangMárcio Weber PaixãoPublished in: RSC advances (2018)
The combination of visible-light and tris(trimethylsilyl)silane promoting intramolecular reductive cyclization protocol for the synthesis of functionalized indolines and 2,3-dihydrobenzofurans has been developed. The transformations occur in the absence of transition metal and additional photocatalyst. In addition, quantum yield ( Φ ) was determined and electron paramagnetic resonance spectroscopy was performed to better understand the reaction pathway.