Investigation of early and lifetime clinical features and comorbidities for the risk of developing treatment-resistant depression in a 13-year nationwide cohort study.

Shiau-Shian HuangHsi-Han ChenJui WangWei J ChenHsi-Chung ChenPo-Hsiu Kuo

Published in: BMC psychiatry (2020)

Our findings indicate the need to monitor early comorbidities and polypharmacy patterns in patients with depression associated with elevated TRD risk.

Keyphrases

depressive symptoms
sleep quality
emergency department
cross sectional
physical activity