The effect of obesity, macronutrients, fasting and nutritional status on drug-metabolizing cytochrome P450s: a systematic review of current evidence on human studies.

Meysam ZarezadehAhmad SaedisomeoliaMahoor ShekarabiMasoud KhorshidiMohammad Reza EmamiDaniel J Müller

Published in: European journal of nutrition (2020)

The activity of drug-metabolizing CYPs are altered by body composition, dietary intake and nutritional status. This relationship might contribute to drug toxicity or reduce treatment efficacy and influence cost-effectiveness of medical care.

Keyphrases

body composition
insulin resistance
endothelial cells
resistance training
bone mineral density
metabolic syndrome
adverse drug
weight loss
weight gain
blood glucose
body mass index
physical activity
pluripotent stem cells
postmenopausal women
high fat diet induced
case control