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Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer.

Kimberley J PerezAnna M ChiarellaJames M ClearyNora HorickColin WeekesThomas AbramsLawrence BlaszkowskyPeter EnzingerMarios GiannakisLipika GoyalJeffrey A MeyerhardtDouglas RubinsonMatthew B YurgelunWolfram GoesslingBruce J GiantonioLauren BraisVictoria GermonDanielle StonelySrivatsan RaghavanBasil BakirKoushik DasJason R PitarresiAndrew J AguirreMichael NeedleAnil K RustgiBrian M Wolpin
Published in: The oncologist (2023)
In this phase Ib trial, ficlatuzumab, gemcitabine, and albumin-bound paclitaxel were associated with durable treatment responses and increased rates of hypoalbuminemia and edema.
Keyphrases
  • locally advanced
  • clinical trial
  • study protocol
  • advanced non small cell lung cancer
  • phase ii
  • randomized controlled trial
  • radiation therapy
  • chemotherapy induced
  • replacement therapy
  • open label