Dectin-1 Acts as a Non-Classical Receptor of Ang II to Induce Cardiac Remodeling.
Shiju YeHe HuangXue HanWu LuoLili WuYang YeYingchao GongXia ZhaoWei-Jian HuangYi WangXiaohong LongGuo-Sheng FuGuang LiangPublished in: Circulation research (2023)
Our study has discovered dectin-1 as a new nonclassical receptor of Ang II and a key player in cardiac remolding and dysfunction. These studies suggest that dectin-1 may be a new target for treating hypertension-related heart failure.