The human, F-actin-based cytoskeleton as a mutagen sensor.
Nicolette M ClarkCarlos A Garcia GalindoVandan K PatelMichele L ParryRebecca J StollJohn M YavorskiElizabeth P PinkasonEdna M JohnsonChelsea M WalkerJoseph JohnsonWade J SextonDomenico CoppolaGeorge BlanckPublished in: Cancer cell international (2017)
Determination of cytoskeletal integrity may provide the opportunity to assess mutation burdens in nonclonal cell populations, such as in intact tissues, where DNA sequencing for heterogeneous mutation burdens can be challenging.