Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease.

Anneleen BerendeLisette NieuwenhuisHadewych J M Ter HofstedeFidel J VosMichiel L VogelaarMirjam TrompHenriët van MiddendorpA Rogier T DondersAndrea W M EversBart Jan KullbergEddy M M Adang

Published in: PloS one (2018)

The longer-term treatments were similar with regard to costs, effectiveness and cost-effectiveness compared to shorter-term treatment in patients with borreliosis-attributed persistent symptoms after one year of follow-up. Given the results of this study, and taking into account the external costs associated with antibiotic resistance, the shorter-term treatment is the antibiotic regimen of first choice.

Keyphrases

preterm infants
gestational age
randomized controlled trial
depressive symptoms
palliative care
combination therapy
preterm birth